College of Science and Health | DePaul University > Faculty & Staff > Faculty A-Z > Eric Norstrom

Eric Norstrom

Classes Taught
  • Cellular Neurobiology (BIO339/439)
  • General Biology for Majors (BIO191)
  • Mammalian Anatomy (BIO201)
  • Topics in Neurobiology (BIO331/431)
  • Brain and Behavior (BIO126)
  • Introduction to Neuroscience (NEU201)
Research Interests

The efforts of Norstrom's research attempt to answer the question: What are the cellular mechanisms of disease states in the brain? His lab is focused on the cellular neurobiology related to neurodegenerative diseases such as Alzheimer’s disease and prion diseases. By studying the molecular function and processing of proteins involved in these diseases, Norstrom hopes to gain insight into their development and, ultimately, add to the knowledge on how to most effectively and safely treat them. To approach these complex themes, Norstrom​ has utilized molecular genetics and protein biochemistry along with proteomics techniques and fluorescence microscopy. Using cell culture techniques and animal models, his lab will continue to elucidate the function and dysfunction of proteins and cells involved in neurodegenerative disease.
 
Select Publications

Norstrom EM, Zhang C, Tanzi R, Sisodia SS. Identification of NEEP21 as an APP-interacting protein in vivo that modulates amyloidogenic processing in vitro. J Neurosci. 2010 Nov 17;30(46):15677-85. 
 
Choi SH, Norstrom EM. Moderate inhibition of gamma-secretase: Is There a Therapeutic Sweet Spot? J. Neurosci., Dec 2007; 27: 13579 - 13580. (Review) 
 
Norstrom EM, Ciaccio M, Wollmann B, Mastrianni J. Cytosolic PrP toxicity is independent of prion replication and propagation. J Virol. 2007 Mar;81(6):2831-7. Epub 2006 Dec 20.
 
Professional Society Memberships
  • Society for Neuroscience
  • American Association for the Advancement of Science
  • American Society for Cell Biology