College of Science and Health > Faculty & Staff > Faculty A-Z > Dorothy Kozlowski

Dorothy Kozlowski

  • dkozlows@depaul.edu
  • Chair and Vincent de Paul Professor, Neuroscience Department
  • ​​PhD      
  • Neuroscience
  • (773) 325-2191
  • ​McGowan North, Room 124       
Classes Taught
  • Neuroscience Research Methods (NEU 280)
  • Neuroscience Capstone (NEU 390)
  • Cognitive Neuroscience (BIO 342) 
  • Behavioral Neuroscience (BIO 340/440)
  • Topics in Neurobiology (BIO 341/441)
  • Biostatistics (BIO 206)
  • Introduction to Pharmacology (BIO 375/475) 
Research Interests
Kozlowski's lab at DePaul University is focused on Traumatic Brain Injury (TBI) in a rodent model. They have examined numerous approaches aimed at repairing the injured brain following TBI including: gene therapy, bone marrow stem cell transplants, endogenous neurogenesis, and physical rehabilitation. Their current emphasis is on using a model of repeat concussions to understand how they are linked to neurodegenerative disease as well as whether APOE4 is a genetic risk factor for brain trauma related neurodegenerative disease. They utilize steretotaxic surgery, quantitative anatomical analysis, and sophisticated behavioral techniques in our studies. Their overall goal is to understand how the brain tries to repair itself, and how external therapies can help the brain do so. Additionally, Dr. Kozlowski is conducting research on the intersection of brain injury and intimate partner violence.
 
Select Publications
Wilson, R.J. Bell, M.R.  Seyburn, S., & Kozlowski D.A. (2023) Repeat subconcussion in the adult rat gives rise to behavioral deficits similar to a single concussion but different depending upon sex. Behavioral Brain Research 438:114206.

Foecking, E.M., Segismundo, A.B., Lotesto, K.M., Westfall, E.J., Bolduan, A.J., Peter, T.K., Wallace, D.G., Kozlowski, D.A., Stubbs, E.B., Marzo, S.J., & Buram, S.C. (2022) Testosterone treatment restores vestibular function by enhancing neuronal survival in an experimental closed-head repetitive mild traumatic brain injury model.  Behavioral Brain Research 433:113998. https://doi.org/10.1016/j.bbr.2022.113998

Maigler, K., Buhr, T., Park, C., Miller, S.A., Kozlowski, D.A., & Marr, R.A. (2021) Assessment of the effects of altered Amyloid-Beta Clearance on behavior following repeat closed-head brain injury in Amyloid-Beta Precursor Protein humanized mice.  Journal of Neurotrauma. 38(5):665-676.

McDaid, J., Briggs, C.A., Barrington, N.M., Peterson, D.A., Kozlowski, D.A. & Stutzmann, G.E. (2021) Sustained hippocampal synaptic pathophysiology following single and repeated closed-head concussive impacts.  Frontiers in Cellular Neuroscience. 15: 652721. doi: 10.3389/fncel.2021.652721

Lifshitz, J. Crabtree-Nelson, S., & Kozlowski, D.A. (2019) Traumatic brain injury in victims of domestic violence.  Journal of Aggression, Maltreatment & Trauma. 28(6):655-659.

Professional Society Membership

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