College of Science and Health > Faculty & Staff > Faculty A-Z > Elizabeth LeClair

Elizabeth E. LeClair

  • Professor, Developmental Biology
  • ​PhD       ​​
  • Biological Sciences
  • (773) 325-7462
  • ​McGowan North, Rooms 107-109       

Classes Taught
  • General Biology II for Science Majors (Bio 192)
  • Epidemiology (Bio 230)
  • Biostatistics (Bio 206)
  • Developmental Biology w/ Lab (Bio 330/430)
  • Histology (Bio 311)
Research Interests

Research scientist in the field of molecular biology, specializing in CRISPR/Cas9-mediated mutation and tagging of cytoskeletal proteins in immune cells and tumors. Currently working in the zebrafish model organism, with previous experience in mouse models and cell lines.

Select Publications

LeClair, EE (2021) The last half-century of fish explant and organ culture.  Zebrafish, doi: 10.1089/zeb.2020.1935

Anderson, RA, Schwalbach KT, Mui, SR, LeClair, EE, Topczewska, JM, Topczewski, J  (2020) Zebrafish models of skeletal dysplasia induced by cholesterol biosynthesis deficiency.  Disease Models & Mechanisms, doi: 10.1242/dmm.042549​

Kell MJ, Riccio RE, Baumgartner EA, Compton ZJ, Pecorin PJ, Mitchell TA, Topczewski J, LeClair EE. (2018) Targeted deletion of the zebrafish actin-bundling protein L-plastin (lcp1). PLoS ONE 13(1): e0190353.  

Figueroa F, Singer SS, LeClair EE. (2015) Making maxillary barbels with a proximal-distal gradient of Wnt signals in matrix-bound mesenchymal cells. Evolution and Development 17(6): 367-379.

Binelli EA, Luna AN, LeClair EE. (2014) Anatomy and ontogeny of a novel hemodynamic organ in zebrafish. Anatomical Record 297(12): 2299-2317.

Professional Activities

I am the principal investigator of a research lab that trains undergraduate and graduate students in molecular biology, anatomy, microscopy and histology technique. The work is supported by the DePaul University Research Council and the National Institutes of Health.

Professional Society Memberships
  • Society for Developmental Biology
  • Zebrafish Disease Models Society (ZDMS)​​